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Clinical Information

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Amplitude Modulated "S-Tones" Can Be Superior to Noise for Tinnitus Reduction

September 2014, American Journal of Audiology
Richard Tyler, et al.

  • This was a multi-center, randomized controlled trial at three leading university and research audiology centers.
  • Purpose was to compare Serenade’s S-Tones vs. broadband (white) Noise in reducing tinnitus loudness.
  • A highly statistically significant benefit (p<0.01) was observed for S-Tone tinnitus perception reduction vs. Noise.
  • This reduction occurred with patients listening to treatment sounds that they deemed soft, or low volume (more than 50% below the patient’s tinnitus.)
  • 2.7 times (270%) more patients had a better tinnitus reduction for S-Tones vs. Noise of those experiencing an effect.
  • S-Tones provided 1.9 times (190%) the amount of tinnitus reduction as Noise within 120 seconds of sound presentation of those experiencing an effect.

Recent evidence has suggested that amplitude modulated tones might have some advantages over broadband noise. 56 subjects were required to listen to ‘S-Tones’ at a carrier frequency matched at the tinnitus pitch (amplitude modulation rate of 40 Hz) and to broadband noise. Subjects rated their tinnitus loudness before, during and after a 120 second duration masker. Results suggested the S-Tones were generally more effective at reducing tinnitus loudness than noise. In about a third (21/56) of the subjects, there was no significant effect from any masker. In other subjects, 54.3% (19/35) showed a greater reduction for the S-Tones, 20% (7/35) showed a greater reduction with the noise, and 25.7% (9/35) showed similar performance between the two stimuli. The S-Tones showed a statistically significant benefit (p<0.01) vs noise at reducing the patient’s tinnitus perception. Using low-level stimuli that were rated much softer than the subjects’ baseline tinnitus, the S-Tones reduced the tinnitus loudness by 1.9 times the amount that noise did (about 28% on average, whereas the noise reduced the tinnitus by about 15%).

We conclude that S-Tones at the tinnitus pitch-match frequency are more likely to be effective than broadband noise at reducing tinnitus loudness.
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Full Article ?

Hypermonitoring-Measuring the Perceptual Mismatch in Tinnitus in Programmed Serenade Devices

Jeff Carroll, PhD
Poster presented at the 6th International NCRAR Conference, Portland Oregon, 2013

  • 122 data points collected.
  • On a scale of 1 (soft) to 10 (loud) most patients judge their tinnitus to be 3.9 points louder than it is when measured objectively. The ability to quantify this sensitivity gives both the patient and the clinician insight into the condition.
  • Serenade is the only device with software that enables hypermonitoring testing.

Poster (PDF) ?
Data Summary (PDF) ?

Temporary Suppression of Tinnitus by Modulated Sounds

Kelly M. Reavis, et al.
April 2012

In April 2012, the Journal of the Association for Research in Otolaryngology (JARO) published the results of a clinical study done at University of California, Irvine. The following is a summary of the key points of that paper, with a link to the abstract at the end of the summary.

Based on a previous observation that "tinnitus can be temporarily abolished by low-rate electric stimulation from a cochlear implant" (Zeng et al. 2011) the authors sought to determine whether a corresponding acoustic stimulation would suppress tinnitus in subjects without cochlear implants… Continue Reading (PDF) ?

Tinnitus Suppression by Low-rate Electric Stimulation and Its Electrophysiological Mechanisms

Zeng FG, Tang Q, Dimitrijevic A, et al.
July 2011

Tinnitus is a phantom sensation of sound in the absence of external stimulation. However, external stimulation, particularly electric stimulation via a cochlear implant, has been shown to suppress tinnitus. Different from traditional methods of delivering speech sounds or high-rate (>2000 Hz) stimulation… Continue Reading (Abstract) ?

Patterned Sound Therapy for the Treatment of Tinnitus

Kelly M. Reavis, Janice E. Chang, Fan-Gang Zeng.
November 2010, The Hearing Journal

Using Sound to Cure Tinnitus

Sound therapy, via either acoustic or electric stimulation, uses external sounds to provide short- and longterm relief from tinnitus. The interactions between external sounds and tinnitus are well established, as the external sounds can not only induce tinnitus, but can alter its perception as well.

Excessive exposure to loud sounds is the single greatest risk associated with tinnitus onset… Continue Reading (PDF) ?

Clinical Sound Therapy - A Short History of Habituation

SoundCure White Paper
June 2012

Tinnitus is an often debilitating condition where a person hears constant noise in his ears that is not present in the environment. Often called “ringing in the ears”, tinnitus can present as a buzzing, or whooshing, or virtually any other type of sound, except speech or music. There is currently no known cure for tinnitus, but many find relief in therapeutic treatment. The most successful treatment for tinnitus is sound therapy… Continue Reading (PDF) ?